Bioinformatics Research:
Protein Folding, Docking and Prediction of Biological Activity

Center for Advanced Bioinformatics Research
South-West University "Neofit Rilski", Blagoevgrad



Work programme - SECOND STAGE

1 Molecular Docking of mu-, delta-and kappa-opioid receptors with selected ligands. 6 Determination of the ligand-receptor complexes and the docking parameters that describe them.
2 Molecular docking of neurotensin receptors with selected ligands. 6 Determination of the ligand-receptor complexes and the docking parameters that describe them.
3 Molecular docking of cannabinoid receptors with selected ligands. 6 Determination of the ligand-receptor complexes and the docking parameters that describe them.
4 Development of a mathematical model for predicting the biological activity using the results of the molecular docking of new ligands. 9 Mathematical model for the prediction of biological activity through the use of the results of the molecular docking of new ligands.
5 Determination of biological activity of the mu-, delta-and kappa-opioid, neurotensin and cannabinoid receptors. 3 Prediction of biological activity through the use of the created model.
6 Organizing webinars. 6 Organization of 3 webinars.
7 Creating an interactive platform where results and expertise of the members of the project will be promoted. 9 Functioning interactive WEB platform.